Oxymetholone (Oxy M50) is a synthetic anabolic steroid developed by Zoltan ’Anadrol Z’ F. 1960. The primary clinical applications include the treatment of osteoporosis and anemia, as well as the stimulation of muscle growth in malnourished or underdeveloped patients. The drug was approved for human use by the FDA. Later, non-steroidal drugs such as Epogen were developed and proved to be more effective as a treatment for anemia and osteoporosis without the side effects of oxymetholone.
The drug remained available despite this and eventually found a new use in the treatment of HIV waste syndrome. Oxymetholone, commonly presented as a 50 mg tablet, is the strongest androgenic steroid available.
Despite very low binding affinity with the androgen receptor, oximetholone is very effective in promoting extensive gains in body mass, mainly by greatly improving protein synthesis. [Citation needed] For this reason, it is often used by bodybuilders and athletes. Many athletes also use oxymetholone as a means of protecting their joints under heavy loads.
Due to the high water resistance that users’ experience with this drug similarly lubricates the joints and protects them from damage.  Oxymetholone is widely considered by bodybuilders to have the strongest anabolic effect of any available oral steroid.